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Helmut Friess Selected Research

Crohn Disease (Crohn's Disease)

1/2024Fractal analysis of extracellular matrix for observer-independent quantification of intestinal fibrosis in Crohn's disease.
11/2021Crohn's disease: a population-based study of surgery in the age of biological therapy.
1/2020Annexin A1 Expression Capacity as a Determinant for Disease Severity in Crohn's Disease.
5/2011Variable impact of CD39 in experimental murine colitis.
4/2007Increase in substance P precursor mRNA in noninflamed small-bowel sections in patients with Crohn's disease.

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Helmut Friess Research Topics

Disease

224Neoplasms (Cancer)
03/2024 - 12/2000
158Pancreatic Neoplasms (Pancreatic Cancer)
10/2023 - 01/2002
76Adenocarcinoma
01/2024 - 04/2002
53Chronic Pancreatitis
06/2020 - 04/2001
29Neoplasm Metastasis (Metastasis)
05/2024 - 01/2002
29Pain (Aches)
06/2020 - 04/2001
20Inflammation (Inflammations)
11/2022 - 04/2001
18Fibrosis (Cirrhosis)
01/2024 - 04/2002
16Pancreatitis
04/2022 - 02/2002
15Carcinogenesis
01/2021 - 01/2002
14Hepatocellular Carcinoma (Hepatoma)
01/2022 - 07/2003
13Wounds and Injuries (Trauma)
02/2024 - 09/2004
13Stomach Neoplasms (Stomach Cancer)
12/2022 - 07/2002
12Hypoxia (Hypoxemia)
01/2021 - 01/2003
12Carcinoma (Carcinomatosis)
01/2021 - 04/2002
11Liver Cirrhosis (Hepatic Cirrhosis)
01/2024 - 07/2003
10Pancreatic Fistula (Pancreatic Fistulas)
12/2020 - 01/2002
8Rectal Neoplasms (Rectal Cancer)
12/2023 - 03/2007
8Cachexia
01/2023 - 08/2005
8Infections
12/2022 - 06/2002
8Colorectal Neoplasms (Colorectal Cancer)
11/2022 - 09/2002
8Esophageal Neoplasms (Esophageal Cancer)
01/2022 - 04/2002
7Surgical Wound Infection
02/2024 - 05/2012
7Disease Progression
06/2021 - 08/2005
7Colonic Neoplasms (Colon Cancer)
10/2018 - 01/2008
6Abscess
06/2023 - 01/2007
6Liver Diseases (Liver Disease)
11/2022 - 06/2008
6Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2022 - 05/2003
5Anastomotic Leak
04/2024 - 03/2011
5Crohn Disease (Crohn's Disease)
01/2024 - 04/2007
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2023 - 01/2004
5Cholangiocarcinoma
01/2023 - 01/2019
5Diabetes Mellitus
06/2020 - 10/2006
5Necrosis
01/2020 - 01/2002
5Ischemia
03/2017 - 09/2006
4Colitis
06/2023 - 09/2009
4Nausea
01/2021 - 03/2006
4Hemorrhage
03/2017 - 01/2006
4Neuritis (Polyneuritis)
01/2013 - 01/2009

Drug/Important Bio-Agent (IBA)

88Messenger RNA (mRNA)IBA
01/2020 - 12/2000
59Proteins (Proteins, Gene)FDA Link
11/2023 - 08/2002
18EnzymesIBA
01/2023 - 04/2002
16Biomarkers (Surrogate Marker)IBA
01/2023 - 12/2006
15GemcitabineFDA Link
01/2022 - 01/2002
14RNA (Ribonucleic Acid)IBA
03/2024 - 04/2002
12Small Interfering RNA (siRNA)IBA
01/2020 - 04/2003
12LigandsIBA
01/2018 - 01/2002
10Fluorouracil (Carac)FDA LinkGeneric
01/2021 - 01/2002
10CytokinesIBA
12/2020 - 01/2003
10Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 09/2002
10Transforming Growth Factor beta (TGF-beta)IBA
04/2010 - 01/2002
9Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2015 - 12/2002
8DNA (Deoxyribonucleic Acid)IBA
01/2023 - 01/2003
7AlbuminsIBA
07/2023 - 03/2004
7C-Reactive ProteinIBA
01/2023 - 01/2008
7CeruletideIBA
01/2019 - 03/2004
7Cisplatin (Platino)FDA LinkGeneric
08/2018 - 05/2004
7Nerve Growth Factor (NGF)IBA
01/2016 - 11/2002
7RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2009 - 04/2002
6Phosphotransferases (Kinase)IBA
12/2020 - 11/2003
6Glucose (Dextrose)FDA LinkGeneric
01/2020 - 03/2003
6Nerve Growth Factors (Neurotrophins)IBA
01/2014 - 11/2003
6Substance PIBA
04/2013 - 04/2001
5GlucocorticoidsIBA
06/2023 - 03/2006
5AntigensIBA
01/2023 - 05/2003
5folfirinoxIBA
01/2021 - 12/2015
5ChemokinesIBA
01/2017 - 09/2006
5matrigelIBA
01/2014 - 07/2004
5NeuropeptidesIBA
04/2013 - 04/2007
5Protein Isoforms (Isoforms)IBA
10/2010 - 10/2002
5Transforming Growth Factor beta1 (TGF beta 1)IBA
02/2005 - 04/2002
4Dextrans (Dextran)FDA Link
06/2023 - 09/2009
4Peptides (Polypeptides)IBA
01/2022 - 01/2004
4Therapeutic UsesIBA
11/2021 - 07/2006
4Leucovorin (Folinic Acid)FDA Link
01/2021 - 09/2010
4Matrix Metalloproteinases (MMPs)IBA
01/2018 - 02/2007
4PeriostinIBA
11/2016 - 04/2007
4Neurotransmitter Agents (Neurotransmitter)IBA
04/2013 - 04/2001
4Chemokine CX3CL1IBA
01/2013 - 03/2009
4Oxygen (Dioxygen)IBA
02/2012 - 01/2003

Therapy/Procedure

86Therapeutics
01/2024 - 09/2002
38Drug Therapy (Chemotherapy)
05/2024 - 01/2002
34Neoadjuvant Therapy
01/2024 - 11/2009
23Pancreatectomy
09/2023 - 12/2003
21Liver Transplantation
01/2022 - 07/2004
16Pancreaticoduodenectomy
11/2021 - 01/2004
8Laparotomy
02/2024 - 03/2011
8Chemoradiotherapy
10/2011 - 03/2004
7Conservative Treatment
12/2022 - 07/2016
7Combined Modality Therapy
11/2022 - 03/2009
7Hepatectomy
01/2022 - 07/2012
7Adjuvant Chemotherapy
01/2022 - 03/2004
7Length of Stay
06/2021 - 11/2005
6Radiotherapy
12/2023 - 09/2003
6Immunotherapy
10/2023 - 08/2005
6Lasers (Laser)
01/2007 - 06/2002
5Operative Surgical Procedures
02/2024 - 01/2004
5Stents
05/2016 - 03/2005
4Esophagectomy
09/2022 - 03/2011
4Gastrectomy
01/2022 - 12/2004